银离子和其它金属离子治疗胃肠疾病

Title:Silver and Other Metals in the Treatment of Gastrointestinal Diseases

Volume: 22 Issue: 32

Author(s): Krzysztof Siczek, Hubert Zatorski and Jakub Fichna

Affiliation:

关键词: 结肠直肠癌，胃肠道，炎症性肠病，微生物群，纳米粒子，银

摘要: Disturbance in the functioning of the gastrointestinal (GI) tract can critically affect the health and even the life of the whole organism. Several factors, both exo- and endogenous may contribute to the dysregulation of homeostasis in the digestive system, including genetic background, ingestion of highly processed food, exposition to environmental pollution or chronic stress, and changes in gut microflora, to name just a few. An important number of these factors rely on metals, which often play a dual, stimulatory and inhibitory role in crucial physiological processes.

In this paper, we focus on the structures incorporating silver, copper and other metals as future drugs against GI diseases. We critically review available literature for their effectiveness and potential application, and discuss clinical relevance of these findings.

Cite this article as:

Krzysztof Siczek, Hubert Zatorski and Jakub Fichna , Silver and Other Metals in the Treatment of Gastrointestinal Diseases, Current Medicinal Chemistry 2015; 22 (32) . https://dx.doi.org/10.2174/0929867322666151001121439