The Use of Mathematical Modelling for Improving the Tissue Engineering of Organs and Stem Cell Therapy

Title:The Use of Mathematical Modelling for Improving the Tissue Engineering of Organs and Stem Cell Therapy

Volume: 11 Issue: 8

Author(s): Greg Lemon, Sebastian Sjoqvist, Mei Ling Lim, Neus Feliu, Alexandra B. Firsova, Risul Amin, Ylva Gustafsson, Annika Stuewer, Elena Gubareva, Johannes Haag, Philipp Jungebluth and Paolo Macchiarini

Affiliation:

Keywords: Regenerative medicine, tissue engineering, stem cell therapy, stem cells, mathematical modelling, computational modelling.

Abstract: Regenerative medicine is a multidisciplinary field where continued progress relies on the incorporation of a diverse set of technologies from a wide range of disciplines within medicine, science and engineering. This review describes how one such technique, mathematical modelling, can be utilised to improve the tissue engineering of organs and stem cell therapy. Several case studies, taken from research carried out by our group, ACTREM, demonstrate the utility of mechanistic mathematical models to help aid the design and optimisation of protocols in regenerative medicine.

Cite this article as:

Lemon Greg, Sjoqvist Sebastian, Lim Ling Mei, Feliu Neus, Firsova B. Alexandra, Amin Risul, Gustafsson Ylva, Stuewer Annika, Gubareva Elena, Haag Johannes, Jungebluth Philipp and Macchiarini Paolo, The Use of Mathematical Modelling for Improving the Tissue Engineering of Organs and Stem Cell Therapy, Current Stem Cell Research & Therapy 2016; 11 (8) . https://dx.doi.org/10.2174/1574888X10666151001115942