Abstract
Wiping out malaria is now the global concern as about three billion people are at risk of malaria infection globally. Despite of extensive research in the field of vaccine development for malaria, till now, no effective vaccine is available for use and hence only antimalarial drugs remain our best hope for both treatment and prevention of malaria. However, emergence and spread of drug resistance has been a major obstacle for the success of malaria elimination globally. This review will summarize the information related to antimalarial drugs, drug development strategies, drug delivery through nanoparticles, few current issues like adverse side effects of most antimalarial drugs, non availability of drugs in the market and use of fake/poor quality drugs that are hurdles to malaria control. As we don’t have any other option in the present scenario, we have to take care of the existing tools and make them available to almost all malaria affected area.
Keywords: Antimalarial drug, development, resistance.
Graphical Abstract
Current Drug Discovery Technologies
Title:Antimalarial Drug: From its Development to Deface
Volume: 12 Issue: 4
Author(s): Tapan Kumar Barik
Affiliation:
Keywords: Antimalarial drug, development, resistance.
Abstract: Wiping out malaria is now the global concern as about three billion people are at risk of malaria infection globally. Despite of extensive research in the field of vaccine development for malaria, till now, no effective vaccine is available for use and hence only antimalarial drugs remain our best hope for both treatment and prevention of malaria. However, emergence and spread of drug resistance has been a major obstacle for the success of malaria elimination globally. This review will summarize the information related to antimalarial drugs, drug development strategies, drug delivery through nanoparticles, few current issues like adverse side effects of most antimalarial drugs, non availability of drugs in the market and use of fake/poor quality drugs that are hurdles to malaria control. As we don’t have any other option in the present scenario, we have to take care of the existing tools and make them available to almost all malaria affected area.
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Cite this article as:
Barik Kumar Tapan, Antimalarial Drug: From its Development to Deface, Current Drug Discovery Technologies 2015; 12 (4) . https://dx.doi.org/10.2174/1570163812666150907100019
DOI https://dx.doi.org/10.2174/1570163812666150907100019 |
Print ISSN 1570-1638 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-6220 |
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