Abstract
In recent years, the pharmacological potential of quinoxalines has received vast interest due to its many applications. This review centers on a critical overview of chemical diversity and physicochemical properties of bioactive quinoxaline libraries. In addition, recent strategies for obtaining structurally diverse quinoxalines using highly selective processes will be discussed.
Keywords: Quinoxaline, heterocycles, C-H activation, drug-likeness, organometallics.
Graphical Abstract
Current Organic Synthesis
Title:Drug Likeness and Selective Functionalization of Quinoxalines
Volume: 12 Issue: 6
Author(s): Samuel R. A. Ferreira, Marcia S. F. Franco, Evelyn M. L. P. Diniz, Flavio da Silva Emery and Giuliano Cesar Clososki
Affiliation:
Keywords: Quinoxaline, heterocycles, C-H activation, drug-likeness, organometallics.
Abstract: In recent years, the pharmacological potential of quinoxalines has received vast interest due to its many applications. This review centers on a critical overview of chemical diversity and physicochemical properties of bioactive quinoxaline libraries. In addition, recent strategies for obtaining structurally diverse quinoxalines using highly selective processes will be discussed.
Export Options
About this article
Cite this article as:
Ferreira R. A. Samuel, Franco S. F. Marcia, Diniz M. L. P. Evelyn, Silva Emery da Flavio and Clososki Cesar Giuliano, Drug Likeness and Selective Functionalization of Quinoxalines, Current Organic Synthesis 2015; 12 (6) . https://dx.doi.org/10.2174/157017941206150828110053
DOI https://dx.doi.org/10.2174/157017941206150828110053 |
Print ISSN 1570-1794 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-6271 |
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
Related Articles
-
Pharmacogenetic Aspects of Therapy with Cholinesterase Inhibitors: The Role of CYP2D6 in Alzheimers Disease Pharmacogenetics
Current Alzheimer Research Endothelins and Nitric Oxide: Vasoactive Modulators of Carotid Body Chemoreception
Current Neurovascular Research Lysosomal Potassium Channels: Potential Roles in Lysosomal Function and Neurodegenerative Diseases
CNS & Neurological Disorders - Drug Targets Imatinib Mesylate: An Innovation in Treatment of Autoimmune Diseases
Recent Patents on Inflammation & Allergy Drug Discovery Cerebrovascular Ultrasonography for Selecting Patients for Stroke Intervention
Recent Patents on CNS Drug Discovery (Discontinued) Early β-Amyloid-induced Synaptic Dysfunction Is Counteracted by Estrogen in Organotypic Hippocampal Cultures
Current Alzheimer Research Serotonin Involvement in the Basal Ganglia Pathophysiology: Could the 5-HT2C Receptor be a New Target for Therapeutic Strategies?
Current Medicinal Chemistry Proteomics in the Discovery of New Therapeutic Targets for Psychiatric Disease
Current Molecular Medicine VaD - An Integrated Framework for Cognitive Rehabilitation
CNS & Neurological Disorders - Drug Targets Dietary Opinion Beyond Biotin Intakes
Current Nutrition & Food Science Quantifying Risk: The Role of Absolute and Relative Measures in Interpreting Risk of Adverse Reactions from Product Labels of Antipsychotic Medications
Current Drug Safety The Effect of Consulting Correct Techniques of Breastfeeding on Treatment of Fissure on the Nipple in Primiparous Mothers Referred to Hamadan Healthcare Centers: A Randomized Controlled Trial Study
Current Women`s Health Reviews Bispidine as a Privileged Scaffold
Current Topics in Medicinal Chemistry Eicosanoid Inhibitors as Therapeutic Targets for Metabolic Syndrome Related Kidney Disease
Current Enzyme Inhibition Psychosocial Predictors of Relapse Among Patients with Alcohol Problems
Current Drug Abuse Reviews Forensic Toxicology and Pharmacogenomics: Hype or Hope For Higher Standards in Forensic Medicine?
Current Pharmacogenomics and Personalized Medicine Schizophrenia and Nicotine Dependence: What Psychopharmacological Treatment Options are Available for the Duo Perturbationes?
Current Drug Targets Lithium and its Neuroprotective and Neurotrophic Effects: Potential Treatment for Post-Ischemic Stroke Sequelae
Current Drug Targets PDE5 Inhibitor Treatment Options for Urologic and Non-Urologic Indications: 2012 Update
Current Pharmaceutical Design “Connecting the Dots” from Blood Brain Barrier Dysfunction to Neuroinflammation and Alzheimer’s Disease
Current Neurovascular Research