Abstract
A convenient and practical approach for the total synthesis of Xestoaminol C has been accomplished with 16.43% overall yield from commercially available D-glucose. The synthesis involves SN2 type centre inversion with azido group, Staudinger reaction, Wittig olefination and Pearlman’s catalytic hydrogenation.
Keywords: Staudinger reaction, Wittig olefination, oxidative cleavage, hydrogenation, D-glucose.
Graphical Abstract
Call for Papers in Thematic Issues
Catalytic C-H bond activation as a tool for functionalization of heterocycles
The major topic is the functionalization of heterocycles through catalyzed C-H bond activation. The strategies based on C-H activation not only provide straightforward formation of C-C or C-X bonds but, more importantly, allow for the avoidance of pre-functionalization of one or two of the cross-coupling partners. The beneficial impact of ...read more
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