Abstract
Proteases are key regulators of many physiological and pathological processes [1,2], and are recognized as important and tractable drug candidates. Consequently, knowledge of protease substrate recognition and specificity promotes identification of biologically relevant substrates, helps elucidating a
Keywords: phage display, matrix metalloproteinases, substrate profiling
Combinatorial Chemistry & High Throughput Screening
Title: Screening for Protease Substrate by Polyvalent Phage Display
Volume: 8 Issue: 2
Author(s): Radislav Sedlacek and Emily Chen
Affiliation:
Keywords: phage display, matrix metalloproteinases, substrate profiling
Abstract: Proteases are key regulators of many physiological and pathological processes [1,2], and are recognized as important and tractable drug candidates. Consequently, knowledge of protease substrate recognition and specificity promotes identification of biologically relevant substrates, helps elucidating a
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Cite this article as:
Sedlacek Radislav and Chen Emily, Screening for Protease Substrate by Polyvalent Phage Display, Combinatorial Chemistry & High Throughput Screening 2005; 8 (2) . https://dx.doi.org/10.2174/1386207053258541
DOI https://dx.doi.org/10.2174/1386207053258541 |
Print ISSN 1386-2073 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5402 |
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