Abstract
A novel one-pot and mild synthesis of benzoimidazole derivatives through the reaction of o-Phenylenediamine with aromatic aldehydes in the presence of MnO2 nanoparticles supported on silica as oxidizing agent under grinding conditions. The significant features of the present protocol are; simplicity of procedure, high products yields, purity of products, solvent-free condition, and easily work-up procedure.
Keywords: Benzoimidazoles, aromatic aldehydes, MnO2 nanoparticles, o-phenylenediamine, synthesis, solvent-free.