Motility Disorders, Functional Gastrointestinal Disorders, Inflammatory Bowel Disease and Cardiac Rhythm Disturbances - Is there a Link? Review of Literature

Title:Motility Disorders, Functional Gastrointestinal Disorders, Inflammatory Bowel Disease and Cardiac Rhythm Disturbances - Is there a Link? Review of Literature

Volume: 16 Issue: 3

Author(s): Michal Zorniak, Marek Waluga and Marek Hartleb

Affiliation:

Keywords: Autonomic nervous system, cardiac arrhtytmia, inflammatory bowel disease, irritable bowel syndrome, proarrhythmic drugs.

Abstract: Gastrointestinal disorders are frequently accompanied by symptoms exceeding gastrointestinal tract. This is at least partially connected with the involvement of autonomic nervous system in pathophysiology of diseases such as inflammatory bowel disease (IBD), irritable bowel syndrome (IBS) or spectrum of motility disorders. In light of the above, involvement of cardiovascular system in natural history of gastrointestinal disorders seems to be of interest. On the other hand, available data regarding the prevalence of cardiac rhythm disturbances in IBD, IBS and motility disorders is limited. What is more, pharmacotherapy of the mentioned diseases includes drugs with possible arrhythmogenic potential. In this review we present current experiences and observations concerning gastrointestinal disorders and cardiac rhythm disturbances.

Cite this article as:

Zorniak Michal, Waluga Marek and Hartleb Marek, Motility Disorders, Functional Gastrointestinal Disorders, Inflammatory Bowel Disease and Cardiac Rhythm Disturbances - Is there a Link? Review of Literature, Current Drug Targets 2015; 16 (3) . https://dx.doi.org/10.2174/1389450116666150304104453