Abstract
Human serum albumin (HSA) is the most abundant protein in plasma, and plays multiple roles in physiology, including as a carrier protein for endogenous and exogenous compounds. Recent studies provide new evidences to support the enzymatic activities of HSA and new molecular insights for such activities. Here, the structural features and enzymatic characteristics of HSA are reviewed.
Keywords: Human serum albumin, structure, drug absorption and distribution, drug metabolism, enzymatic activity, esterase-like activity, peroxidase activity, glycation.
Current Pharmaceutical Design
Title:Structure and Enzymatic Activities of Human Serum Albumin
Volume: 21 Issue: 14
Author(s): Yu Wang, Shihua Wang and Mingdong Huang
Affiliation:
Keywords: Human serum albumin, structure, drug absorption and distribution, drug metabolism, enzymatic activity, esterase-like activity, peroxidase activity, glycation.
Abstract: Human serum albumin (HSA) is the most abundant protein in plasma, and plays multiple roles in physiology, including as a carrier protein for endogenous and exogenous compounds. Recent studies provide new evidences to support the enzymatic activities of HSA and new molecular insights for such activities. Here, the structural features and enzymatic characteristics of HSA are reviewed.
Export Options
About this article
Cite this article as:
Wang Yu, Wang Shihua and Huang Mingdong, Structure and Enzymatic Activities of Human Serum Albumin, Current Pharmaceutical Design 2015; 21 (14) . https://dx.doi.org/10.2174/1381612821666150302113906
DOI https://dx.doi.org/10.2174/1381612821666150302113906 |
Print ISSN 1381-6128 |
Publisher Name Bentham Science Publisher |
Online ISSN 1873-4286 |
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
- Announcements
Related Articles
-
Long Term Regulation of Cardiac L-Type Calcium Channel by Small G Proteins
Current Medicinal Chemistry Sulfonated Carbon/Silica Composites: Highly Efficient Heterogeneous Catalysts for the One-Pot Synthesis of Hantzsch 1,4-dihydropyridines, 2,4,5-trisubstituted Imidazoles and 2-arylbenzimidazoles
Current Catalysis Patent Selections
Recent Patents on Biomarkers Editorial [Hot Topic: Modifying Cardiovascular Risk Factors: Epidemiology and Characteristics of Hypertension-Related Disorders (Executive Guest Editor: Aurelio Leone)]
Current Pharmaceutical Design C-type Natriuretic Peptide (CNP): Cardiovascular Roles and Potential as a Therapeutic Target
Current Pharmaceutical Design Targeting Peroxisome Proliferator-Activated Receptor Gamma for Generation of Antidiabetic Drug
Current Diabetes Reviews Endothelial Dysfunction, Impaired Endogenous Platelet Inhibition and Platelet Activation in Diabetes and Atherosclerosis
Current Vascular Pharmacology Targeting Transient Receptor Potential Channels in Cardiometabolic Diseases and Myocardial Ischemia Reperfusion Injury
Current Drug Targets Pexelizumab, an Anti-C5 Complement Antibody for Primary Coronary Revascularization: A New Insight from Old Versions
Cardiovascular & Hematological Disorders-Drug Targets Validation of a Rapid and Sensitive HPLC-UV Method for the Quantification of Eprosartan Mesylate in Bulk Drug, TeventenTM and Ultradeformable Lipid Based Vesicular System
Current Pharmaceutical Analysis Exploring Newer Target Sodium Glucose Transporter 2 for the Treatment of Diabetes Mellitus
Mini-Reviews in Medicinal Chemistry Impact of Traditional Therapies and Biologics on Cardiovascular Diseases in Rheumatoid Arthritis
Current Vascular Pharmacology Epinephrine and its Role in the Development of Obesity and Hypertension
Current Hypertension Reviews Novel Drug Targets for the Treatment of Cardiac Diseases
Current Pharmacogenomics and Personalized Medicine Apoptosis in Atherosclerosis: Virtue or Vice
Current Cardiology Reviews Statins and Protein Prenylation in Cancer Cell Biology and Therapy
Anti-Cancer Agents in Medicinal Chemistry Iontophoresis: Drug Delivery System by Applying an Electrical Potential Across the Skin
Drug Delivery Letters Stage A: Can Heart Failure Be Prevented?
Current Cardiology Reviews Q Fever Endocarditis
Infectious Disorders - Drug Targets Third and Fourth Generation Fluoroquinolone Antibacterials: A Systematic Review of Safety and Toxicity Profiles
Current Drug Safety