摘要
Satureja montana L. 和 唇形科S. subspicata Vis. 广泛应用于淋巴结及呼吸系统炎症的愈合,在 Balcanic传统医学中已被应用几百年。本文对克罗地亚 S. montana 和S. Subspicata7个物种样品和总酚类和总黄酮类化合物(利用UV/Vis进行分析)、酚类化合物(利用HPLC进行分析)、抗菌和抗氧化活性进行研究。利用HPLC对甲醇和乙醇萃取物中的八种酚类化合物(芦丁、槲皮素、咖啡酸、对香酸,鞣花酸,原儿茶酸,迷迭香酸和丁香酸)进行鉴定和定量分析。结果表明两物种都含有多酚和其它具有螯合作用和自由基清除能力的抗氧化成分。从这两个物种的提取物对体外测试的微生物种类(金黄色葡萄球菌、白色念珠菌、都柏林念珠菌、光滑念珠菌、克柔念珠菌、光滑念珠菌、近平滑念珠菌和石膏样小孢子菌)具有广谱的抗菌活性。
关键词: 抗菌活性,抗氧化能力,酚类化合物,Satureja montana
图形摘要
Current Drug Targets
Title:Antimicrobial and Antioxidant Properties of Satureja Montana L. and S. Subspicata Vis. (Lamiaceae)
Volume: 16 Issue: 14
Author(s): Dario Kremer, Iztok Jože Košir, Marijana Zovko Končić, Andreja Čerenak, Tanja Potočnik, Siniša Srečec, Marko Randić and Ivan Kosalec
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关键词: 抗菌活性,抗氧化能力,酚类化合物,Satureja montana
摘要: Satureja montana L. and S. subspicata Vis. (Lamiaceae) are used for centuries in traditional medicine of Balcanic people in the healing of the lymphatic nodule and respiratory system inflammation. In this paper the amount of total phenols and flavonoids (analyzed by UV/Vis spectrophotometry), phenolic compounds profile (analyzed by HPLC), antimicrobial and antioxidant activities were studied in samples collected in seven per species populations of S. montana and S. subspicata in Croatia. Eight phenolic compounds (rutin, quercetin, caffeic, p-coumaric, ellagic, protocatehuic, rosmarinic, and syringic acid) were identified and quantified using HPLC in methanolic and ethanolic extracts. Results showed that both species contained polyphenolics and other antioxidant compounds with chelating and radical-scavenging properties. The extracts prepared from both species showed broad spectrum of antimicrobial activity on in vitro tested microbial species (Staphylococcus aureus, Escherichia coli, Candida albicans, C. dubliniensis, C. krusei, C. glabrata, C. parapsilosis, and Microsporum gypseum).
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Dario Kremer, Iztok Jože Košir, Marijana Zovko Končić, Andreja Čerenak, Tanja Potočnik, Siniša Srečec, Marko Randić and Ivan Kosalec , Antimicrobial and Antioxidant Properties of Satureja Montana L. and S. Subspicata Vis. (Lamiaceae), Current Drug Targets 2015; 16 (14) . https://dx.doi.org/10.2174/1389450116666150202161926
DOI https://dx.doi.org/10.2174/1389450116666150202161926 |
Print ISSN 1389-4501 |
Publisher Name Bentham Science Publisher |
Online ISSN 1873-5592 |
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