A Rapid Tandem Knoevenagel/Michael Reaction Using Mohr’s Salt as a Highly Efficient Catalyst: Green Synthesis of Bis(pyrazolyl)methanes

Title:A Rapid Tandem Knoevenagel/Michael Reaction Using Mohr’s Salt as a Highly Efficient Catalyst: Green Synthesis of Bis(pyrazolyl)methanes

Volume: 12 Issue: 1

Author(s): Khalil Eskandari, Bahador Karami, Saeed Khodabakhshi and Mahnaz Farahi

Affiliation:

Keywords: Green synthesis, Knoevenagel condensation, Michael addition, aqueous media, bis(pyrazolyl)methane, Mohr’s salt.

Abstract: A convenient access to some new and known bis(pyrazolyl)methanes synthesis has been successfully achieved via an alternative Knoevenagel/Michael reaction of aromatic aldehydes and pyrazole-5-one in the presence of Mohr’s salt as a green catalyst. This novel procedure has some advantages such as high efficiency, simplicity, high rate and environmental safety.

Cite this article as:

Eskandari Khalil, Karami Bahador, Khodabakhshi Saeed and Farahi Mahnaz, A Rapid Tandem Knoevenagel/Michael Reaction Using Mohr’s Salt as a Highly Efficient Catalyst: Green Synthesis of Bis(pyrazolyl)methanes, Letters in Organic Chemistry 2015; 12 (1) . https://dx.doi.org/10.2174/1570178612666141204224826