Abstract
Various biomedical applications that use Fe3O4 magnetic nanoparticles, both for diagnostic or/and therapy have been described. This review summarizes the most common synthesis methods for Fe3O4 nanoparticles, recently used for developing applications which improve the cancer treatment. We emphasize the tumor targeting possibilities for such systems, the magnetic hyperthermia and controlled delivery of anti-tumor, focusing on Fe3O4-based systems for osteosarcoma treatment using Doxorubicin as chemotherapeutic agent.
Keywords: Cancer therapy, drug delivery systems, Fe3O4, hyperthermia, magnetite, nanomedicine, targeting.
Graphical Abstract
Current Proteomics
Title:Magnetite Nanostructures with Applications in Cancer Therapy
Volume: 11 Issue: 2
Author(s): Roxana Cristina Popescu and Alexandru Mihai Grumezescu
Affiliation:
Keywords: Cancer therapy, drug delivery systems, Fe3O4, hyperthermia, magnetite, nanomedicine, targeting.
Abstract: Various biomedical applications that use Fe3O4 magnetic nanoparticles, both for diagnostic or/and therapy have been described. This review summarizes the most common synthesis methods for Fe3O4 nanoparticles, recently used for developing applications which improve the cancer treatment. We emphasize the tumor targeting possibilities for such systems, the magnetic hyperthermia and controlled delivery of anti-tumor, focusing on Fe3O4-based systems for osteosarcoma treatment using Doxorubicin as chemotherapeutic agent.
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Cite this article as:
Popescu Cristina Roxana and Grumezescu Mihai Alexandru, Magnetite Nanostructures with Applications in Cancer Therapy, Current Proteomics 2014; 11 (2) . https://dx.doi.org/10.2174/157016461102140917122621
DOI https://dx.doi.org/10.2174/157016461102140917122621 |
Print ISSN 1570-1646 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-6247 |
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