Synthesis of Allosamidin and its Analogues

Gangliang      Huang; Qilin      Tang

doi:10.2174/1570179411666140623223120

Abstract

The pseudo-trisaccharide allosamidin 1 is a potent inhibitor of all family 18 chitinases, and it is confirmed to have biological activities against insects and fungi. The solid/liquid phase syntheses of allosamidin 1 and its analogues have been developed in recent years, and these compounds can be obtained by iterative glycosylation reactions, catalytic hydrogenation, acetylation, deacetylation, or photolysis, respectively.

Keywords: Allosamidin, analogues, recent development, synthesis.

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Current Organic Synthesis

Title:Synthesis of Allosamidin and its Analogues

Volume: 11 Issue: 5

Author(s): Gangliang Huang and Qilin Tang

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Keywords: Allosamidin, analogues, recent development, synthesis.

Abstract: The pseudo-trisaccharide allosamidin 1 is a potent inhibitor of all family 18 chitinases, and it is confirmed to have biological activities against insects and fungi. The solid/liquid phase syntheses of allosamidin 1 and its analogues have been developed in recent years, and these compounds can be obtained by iterative glycosylation reactions, catalytic hydrogenation, acetylation, deacetylation, or photolysis, respectively.

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Huang Gangliang and Tang Qilin, Synthesis of Allosamidin and its Analogues, Current Organic Synthesis 2014; 11 (5) . https://dx.doi.org/10.2174/1570179411666140623223120

DOI https://dx.doi.org/10.2174/1570179411666140623223120	Print ISSN 1570-1794
Publisher Name Bentham Science Publisher	Online ISSN 1875-6271