硼酸类酶抑制剂：最近研究进展的综述

Title:Boronic Acid-based Enzyme Inhibitors: A Review of Recent Progress

Volume: 21 Issue: 28

Author(s): H. Fu, H. Fang, Jie Sun, H. Wang, A. Liu, J. Sun and Z. Wu

Affiliation:

关键词: 硼酸，硼替佐米，酶抑制剂，组蛋白去乙酰化酶，蛋白酶体抑制剂，丝氨酸蛋白酶

摘要: Since Bortezomib was approved by US FDA as the first drug to treat multiple myeloma, various boronic acid compounds have been developed as enzyme inhibitors. This paper reviewed the progress of boronic acid-based inhibitors against enzymes including proteasome, serine protease, HDACs and other enzymes in the past decade.

Cite this article as:

Fu H., Fang H., Sun Jie, Wang H., Liu A., Sun J. and Wu Z., Boronic Acid-based Enzyme Inhibitors: A Review of Recent Progress, Current Medicinal Chemistry 2014; 21 (28) . https://dx.doi.org/10.2174/0929867321666140601200803