Abstract
The present study was aimed at assessing the anti-depressant activity of the alcoholic extracts of the leaves of Alternanthera sessilis and Clerodendrum infortunatum. The activity was studied on Swiss Albino mice using the Tail Suspension Test and the Forced Swim Test, at doses of 100mg/kg b.w. and 20 mg/kg b.w. with Diazepam as the standard drug. Both the extracts, at higher dose, exhibited significant reduction in the duration of immobility. The alcoholic extract of Clerodendrum infortunatum was the most active extract in both the animal models, at a dose of 200 mg/kg b.w. Thus this study verifies the claims of antidepressant activity of these plants in the tradional medicine.
Keywords: Alternanthera sessilis, anti-depressant, clerodendrum infortunatum.
Related Journals
Anti-Cancer Agents in Medicinal Chemistry
Current Analytical Chemistry
Current Computer-Aided Drug Design
Current Bioactive Compounds
Combinatorial Chemistry & High Throughput Screening
Current Organic Chemistry
Current Medicinal Chemistry
Current Organic Synthesis
Central Nervous System Agents in Medicinal Chemistry
Mini-Reviews in Organic Chemistry
Related Books
2-Deoxy-D-Glucose: Chemistry and Biology
Chiral Ionic Liquids: Applications in Chemistry and Technology
Therapeutic Insights into Herbal Medicine through the Use of Phytomolecules
Biochar - Solid Carbon for Sustainable Agriculture
DFT-Based Studies On Atomic Clusters
Basics of Organic Chemistry: A Textbook for Undergraduate Students
Science of Spices and Culinary Herbs - Latest Laboratory, Pre-clinical, and Clinical Studies
Hydrotalcite-based Materials: Synthesis, Characterization and Application
The 2-Dimensional World of Graphene
Advances in Dye Degradation
28