Abstract
In this work, an overview of analytical methods employing derivatization reactions in chemiluminescence detection is presented. Method development, instrumental configurations and hyphenated manifolds, specifically designed or implemented to accommodate CL detection, along with their analytical applications for the determination of a wide variety of organic compounds such as biochemically active substances, pharmaceutical active compounds, environmental pollutants and food constituents, are summarized. The analytical merits of derivatization reactions in chemiluminescence analysis and their potential for the development of sensitive and selective methods are elucidated.
Keywords: Chemiluminescence, derivatization, liquid chromatography, capillary electrophoresis.
Graphical Abstract
Current Analytical Chemistry
Title:Derivatization Coupled to Chemiluminescence Detection
Volume: 10 Issue: 3
Author(s): George Z. Tsogas, Dimosthenis L. Giokas and Athanasios G. Vlessidis
Affiliation:
Keywords: Chemiluminescence, derivatization, liquid chromatography, capillary electrophoresis.
Abstract: In this work, an overview of analytical methods employing derivatization reactions in chemiluminescence detection is presented. Method development, instrumental configurations and hyphenated manifolds, specifically designed or implemented to accommodate CL detection, along with their analytical applications for the determination of a wide variety of organic compounds such as biochemically active substances, pharmaceutical active compounds, environmental pollutants and food constituents, are summarized. The analytical merits of derivatization reactions in chemiluminescence analysis and their potential for the development of sensitive and selective methods are elucidated.
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Cite this article as:
Tsogas Z. George, Giokas L. Dimosthenis and Vlessidis G. Athanasios, Derivatization Coupled to Chemiluminescence Detection, Current Analytical Chemistry 2014; 10 (3) . https://dx.doi.org/10.2174/1573411010999131219101823
DOI https://dx.doi.org/10.2174/1573411010999131219101823 |
Print ISSN 1573-4110 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-6727 |
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