Synthesis of Alkaloids: Recent Advances in the Synthesis of Phenanthroindolizidine Alkaloids

Title:Synthesis of Alkaloids: Recent Advances in the Synthesis of Phenanthroindolizidine Alkaloids

Volume: 14 Issue: 2

Author(s): Antonio C. B. Burtoloso, Ariane F. Bertonha and Isac G. Rosset

Affiliation:

Keywords: Alkaloids, antofine, anticancer, anti-inflammatory, antifungal, antibacterial, biaryl coupling, indolizidines, phenanthroindolizidines, total synthesis, typlophorine, tylocrebrine.

Abstract: Phenanthroindolizidine alkaloids are a well-known class of compounds due to their interesting biological activities, especially anticancer ones. Represented by more than 60 substances, they are mainly isolated from plants of the Moraceae and Asclepiadaceae families. In the last 30 years, a great effort has been made aiming the synthesis of these compounds and analogues to be applied in medicinal chemistry.

Cite this article as:

Burtoloso C. B. Antonio, Bertonha F. Ariane and Rosset G. Isac, Synthesis of Alkaloids: Recent Advances in the Synthesis of Phenanthroindolizidine Alkaloids, Current Topics in Medicinal Chemistry 2014; 14 (2) . https://dx.doi.org/10.2174/1568026613666131213154633