Green Synthesis of Novel Phthalimide Derivatives of Aspirin and P-aminosalicylic Acid as Potential Analgesic- antipyretic and Anti-tuberculosis Agents

Title:Green Synthesis of Novel Phthalimide Derivatives of Aspirin and P-aminosalicylic Acid as Potential Analgesic- antipyretic and Anti-tuberculosis Agents

Volume: 11 Issue: 4

Author(s): Yervala D. Reddy, Chittireddy V.R. Reddy and Pramod K. Dubey

Affiliation:

Keywords: Phthalic anhydrides, p-aminosalicylic acid, analgesic, antipyretic & anti-tuberculosis agents.

Abstract: Green synthesis of novel compounds 4-(2-carboxybenzamido)-2-hydroxybenzoic acids 3a-3e, 4-(1, 3- dioxoisoindolin-2-yl)-2-hydroxybenzoic acids 4a-4e, 2-acetoxy-4-(2-carboxybenzoylamino)benzoic acids 6a-6e and 2- acetoxy-4-(1, 3-dioxo-1, 3-dihydroisoindol-2-yl)-benzoic acids 8a-8e has been developed which were analogs of aspirin (used as analgesic, anti-pyretic and cardiovascular drug) and para-aminosalicylic acid ( used as anti-tuberculosis agent).

Cite this article as:

Reddy D. Yervala, Reddy V.R. Chittireddy and Dubey K. Pramod, Green Synthesis of Novel Phthalimide Derivatives of Aspirin and P-aminosalicylic Acid as Potential Analgesic- antipyretic and Anti-tuberculosis Agents, Letters in Organic Chemistry 2014; 11 (4) . https://dx.doi.org/10.2174/1570178610666131210234152