Unequivocal Role of Pyrazine Ring in Medicinally Important Compounds: A Review

Title:Unequivocal Role of Pyrazine Ring in Medicinally Important Compounds: A Review

Volume: 13 Issue: 11

Author(s): Pankaj B. Miniyar, Prashant R. Murumkar, Pallavi S. Patil, Mahesh A. Barmade and Kailash G. Bothara

Affiliation:

Keywords: Pyrazine, anti-tubercular agents, anticancer agents, diuretics, anti-diabetic agents.

Abstract: Pyrazine is one of the important class of heterocyclic compounds that can be obtained naturally or synthesized chemically. Pyrazine ring has got importance in exhibiting various biological activities in association with other scaffolds like pyrrole, pyrazole, imidazole, triazole, tetrazole, thiophene, oxazole, pyridine, piperidine and piperazine. Presence of pyrazine ring as a basic scaffold in various clinically used drugs exhibits its importance in drug design. In this review, attempt has been made to disclose various therapeutic applications of pyrazine derivatives reported during the last decade.

Cite this article as:

Miniyar B. Pankaj, Murumkar R. Prashant, Patil S. Pallavi, Barmade A. Mahesh and Bothara G. Kailash, Unequivocal Role of Pyrazine Ring in Medicinally Important Compounds: A Review, Mini-Reviews in Medicinal Chemistry 2013; 13 (11) . https://dx.doi.org/10.2174/1389557511313110007