Synthesis and Characterization of Novel Peptido Calixarene Dimers

Reza      Zadmard; Malihe      Hajiramezanali

doi:10.2174/15701786113109990022

Abstract

Aniliniumcalix[4]arene dimers with peptide bridges to increase hydrogen bonding between amino acids and nucleic acid bases have been synthesized. Three different kinds of peptide bridges containing L-Alanine, L-Phenylalanine, and L-Tyrosine were prepared by liquid phase peptide synthesis. The dimers were characterized by NMR, MS and ESIMS spectrometry.

Keywords: Calix[4]arene, Dimer, Peptide bridges, Amino acid, Coupling reagent.

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Letters in Organic Chemistry

Title:Synthesis and Characterization of Novel Peptido Calixarene Dimers

Volume: 10 Issue: 8

Author(s): Reza Zadmard and Malihe Hajiramezanali

Affiliation:

Keywords: Calix[4]arene, Dimer, Peptide bridges, Amino acid, Coupling reagent.

Abstract: Aniliniumcalix[4]arene dimers with peptide bridges to increase hydrogen bonding between amino acids and nucleic acid bases have been synthesized. Three different kinds of peptide bridges containing L-Alanine, L-Phenylalanine, and L-Tyrosine were prepared by liquid phase peptide synthesis. The dimers were characterized by NMR, MS and ESIMS spectrometry.

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Zadmard Reza and Hajiramezanali Malihe, Synthesis and Characterization of Novel Peptido Calixarene Dimers, Letters in Organic Chemistry 2013; 10 (8) . https://dx.doi.org/10.2174/15701786113109990022