Abstract
The focus of the review is on the formation of multiple bonds by palladium catalyzed C-H activation and functionalization. These include alkanylation, alkenylation, arylations, annulations, domino, cascade reaction, coupling and synthesis of spiro compounds. The non-synchronous formation of new carbon-carbon and carbon-heteroatom (N, O) bonds for the construction of various heterocycles is also discussed.
Keywords: C-H activation, Non synchronous Multiple-bond formation, Palladium catalysis, Coupling reactions, Domino reactions, Heterocycles.
Current Organic Chemistry
Title:Palladium Catalyzed C–H Activation and its Application to Multi-bond Forming Reactions
Volume: 17 Issue: 18
Author(s): Krishnan Ramachandiran, Thonthula Sreelatha, Neelakandan V. Lakshmi, Thelagathoti H. Babu, Doraiswamy Muralidharan and Paramasiram T. Perumal
Affiliation:
Keywords: C-H activation, Non synchronous Multiple-bond formation, Palladium catalysis, Coupling reactions, Domino reactions, Heterocycles.
Abstract: The focus of the review is on the formation of multiple bonds by palladium catalyzed C-H activation and functionalization. These include alkanylation, alkenylation, arylations, annulations, domino, cascade reaction, coupling and synthesis of spiro compounds. The non-synchronous formation of new carbon-carbon and carbon-heteroatom (N, O) bonds for the construction of various heterocycles is also discussed.
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Ramachandiran Krishnan, Sreelatha Thonthula, Lakshmi V. Neelakandan, Babu H. Thelagathoti, Muralidharan Doraiswamy and Perumal T. Paramasiram, Palladium Catalyzed C–H Activation and its Application to Multi-bond Forming Reactions, Current Organic Chemistry 2013; 17 (18) . https://dx.doi.org/10.2174/13852728113179990094
DOI https://dx.doi.org/10.2174/13852728113179990094 |
Print ISSN 1385-2728 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5348 |
Call for Papers in Thematic Issues
Catalytic C-H bond activation as a tool for functionalization of heterocycles
The major topic is the functionalization of heterocycles through catalyzed C-H bond activation. The strategies based on C-H activation not only provide straightforward formation of C-C or C-X bonds but, more importantly, allow for the avoidance of pre-functionalization of one or two of the cross-coupling partners. The beneficial impact of ...read more
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