A Facile and Convenient Approach for the One-Pot Synthesis of Naphtho- 1,3-oxazine Derivatives

Santosh      V. Goswami; Sunil      S. Wagh; Shrikant      S. Pendalwar; Sudhakar      R. Bhusare

doi:10.2174/22115447113029990012

Abstract

A protocol describes the synthesis of naphtha-1,3-oxaizine derivatives via one-pot multi-component reaction of α-naphthol, formaldehyde and various substituted anilines catalyzed by L-proline as an efficient catalyst. A method offers delightful advantages such as mild reaction conditions, environmentally benign, easy experimental workup and good to excellent yields.

Keywords: Naphthoxazine, α-Naphthol, Formaldehyde, Aniline, L-proline.

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Current Catalysis

Title:A Facile and Convenient Approach for the One-Pot Synthesis of Naphtho- 1,3-oxazine Derivatives

Volume: 2 Issue: 3

Author(s): Santosh V. Goswami, Sunil S. Wagh, Shrikant S. Pendalwar and Sudhakar R. Bhusare

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Keywords: Naphthoxazine, α-Naphthol, Formaldehyde, Aniline, L-proline.

Abstract: A protocol describes the synthesis of naphtha-1,3-oxaizine derivatives via one-pot multi-component reaction of α-naphthol, formaldehyde and various substituted anilines catalyzed by L-proline as an efficient catalyst. A method offers delightful advantages such as mild reaction conditions, environmentally benign, easy experimental workup and good to excellent yields.

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V. Goswami Santosh, S. Wagh Sunil, S. Pendalwar Shrikant and R. Bhusare Sudhakar, A Facile and Convenient Approach for the One-Pot Synthesis of Naphtho- 1,3-oxazine Derivatives, Current Catalysis 2013; 2 (3) . https://dx.doi.org/10.2174/22115447113029990012