Abstract
Diabetic retinopathy affects one-third of people with diabetes and is the most frequent cause of blindness in working aged adults. Although diabetic retinopathy blindness appears to have fallen in the developed world, the rapidly increasing number of persons with diabetes worldwide has resulted in a continuous increase in the global burden of this disease. The major risk factors for diabetic retinopathy include duration of diabetes, hyperglycemia, and hypertension, but this is accountable for only a small amount of the variation in the risk of diabetic retinopathy. Research into new markers for retinopathy including genetics, blood biomarkers and retinal imaging will further improve our understanding of the risk factors and pathogenesis of diabetic retinopathy.
Keywords: Diabetic retinopathy, epidemiology, genetics, biological markers, risk factors.
Current Medicinal Chemistry
Title:Traditional and Novel Risk Factors of Diabetic Retinopathy and Research Challenges
Volume: 20 Issue: 26
Author(s): Gavin S. Tan, M. Kamran Ikram and Tien Y. Wong
Affiliation:
Keywords: Diabetic retinopathy, epidemiology, genetics, biological markers, risk factors.
Abstract: Diabetic retinopathy affects one-third of people with diabetes and is the most frequent cause of blindness in working aged adults. Although diabetic retinopathy blindness appears to have fallen in the developed world, the rapidly increasing number of persons with diabetes worldwide has resulted in a continuous increase in the global burden of this disease. The major risk factors for diabetic retinopathy include duration of diabetes, hyperglycemia, and hypertension, but this is accountable for only a small amount of the variation in the risk of diabetic retinopathy. Research into new markers for retinopathy including genetics, blood biomarkers and retinal imaging will further improve our understanding of the risk factors and pathogenesis of diabetic retinopathy.
Export Options
About this article
Cite this article as:
Tan S. Gavin, Ikram Kamran M. and Wong Y. Tien, Traditional and Novel Risk Factors of Diabetic Retinopathy and Research Challenges, Current Medicinal Chemistry 2013; 20 (26) . https://dx.doi.org/10.2174/09298673113209990023
DOI https://dx.doi.org/10.2174/09298673113209990023 |
Print ISSN 0929-8673 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-533X |
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
- Announcements
Related Articles
-
Animal Models of Obesity and Metabolic Syndrome: Potential Tools for Alzheimers Disease Research
Current Alzheimer Research Editorial (Thematic Issue: Therapies Targeting Oxidative Stress for Human Diseases: Where Are We Now?)
Current Pharmaceutical Biotechnology Impact of Angiotensin Converting Enzyme Inhibitors/Angiotensin Receptors Blockers on Mortality in Acute Heart Failure Patients with Left Ventricular Systolic Dysfunction in the Middle East: Observations from the Gulf Acute Heart Failure Registry (Gulf CARE)
Current Vascular Pharmacology Targeting Bacterial Metalloenzymes: A New Strategy for the Development of Anti-Infective Agents
Anti-Infective Agents in Medicinal Chemistry The Important Role of Potatoes, An Underrated Vegetable Food Crop in Human Health and Nutrition
Current Nutrition & Food Science Toxicology of Trastuzumab: An Insight into Mechanisms of Cardiotoxicity
Current Cancer Drug Targets Prevalence and Clinical Profile of Undiagnosed Diabetes Mellitus: Data from a Tertiary Hospital
Endocrine, Metabolic & Immune Disorders - Drug Targets Erythropoietin in Heart Failure and Other Cardiovascular Diseases: Hematopoietic and Pleiotropic Effects
Current Drug Targets - Cardiovascular & Hematological Disorders The Role of Venous Abnormalities in Neurological Disease
Reviews on Recent Clinical Trials Editorial [Hot topic: Hypertension and Diabetes (Guest Editor: Kazuko Masuo)]
Current Hypertension Reviews Triglyceride Level Affecting Shared Susceptibility Genes in Metabolic Syndrome and Coronary Artery Disease
Current Medicinal Chemistry Meet Our Editorial Board Member:
Current Vascular Pharmacology Editorial [Hot Topic Management of Perioperative Systemic Inflammation During Cardiopulmonary Bypass: We Need a Multimodal Approach (Guest Editor: David Faraoni)]
Recent Patents on Cardiovascular Drug Discovery Novel Orphan Nuclear Receptors-Coregulator Interactions Controlling Anti-Cancer Drug Metabolism
Current Drug Metabolism Hydrolyzates of Silkworm Pupae (Bombyx Mori) Protein is a New Source of Angiotensin I-Converting Enzyme Inhibitory Peptides(ACEIP)
Current Pharmaceutical Biotechnology Regulation of the Sodium-Phosphate Cotransporter Pit-1 and its Role in Vascular Calcification
Current Vascular Pharmacology Mineralocorticoid Receptor Antagonism and Cardiac Remodeling in Ischemic Heart Failure
Current Medicinal Chemistry - Cardiovascular & Hematological Agents Contextualizing Genetics for Regional Heart Failure Care
Current Cardiology Reviews New Insight Into A1 Adenosine Receptors in Diabetes Treatment
Current Pharmaceutical Design Role of Hydrogen Sulfide in Systemic and Pulmonary Hypertension: Cellular Mechanisms and Therapeutic Implications
Cardiovascular & Hematological Agents in Medicinal Chemistry