Abstract
One-pot synthesis of 2-azetidinones has efficiently been carried out in excellent yields by treatment of imines and substituted acetic acids with 3,5-dinitrobenzoyl chloride in the presence of triethylamine. The method is remarkably convenient and pure products were obtained by simple crystallization.
Keywords: β-Lactam, 2-Azetidinone, Staudinger reaction, 3, 5-Dinitrobenzoyl chloride, Ketene, Imine.
Letters in Organic Chemistry
Title:A Simple and Highly Efficient Procedure for One-Pot Synthesis of 2- Azetidinones Using 3,5-Dinitrobenzoyl Chloride
Volume: 10 Issue: 9
Author(s): Alireza Darvishi, Maaroof Zarei and Mohammad Reza Akhgara
Affiliation:
Keywords: β-Lactam, 2-Azetidinone, Staudinger reaction, 3, 5-Dinitrobenzoyl chloride, Ketene, Imine.
Abstract: One-pot synthesis of 2-azetidinones has efficiently been carried out in excellent yields by treatment of imines and substituted acetic acids with 3,5-dinitrobenzoyl chloride in the presence of triethylamine. The method is remarkably convenient and pure products were obtained by simple crystallization.
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Cite this article as:
Darvishi Alireza, Zarei Maaroof and Akhgara Reza Mohammad, A Simple and Highly Efficient Procedure for One-Pot Synthesis of 2- Azetidinones Using 3,5-Dinitrobenzoyl Chloride, Letters in Organic Chemistry 2013; 10 (9) . https://dx.doi.org/10.2174/15701786113109990037
DOI https://dx.doi.org/10.2174/15701786113109990037 |
Print ISSN 1570-1786 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-6255 |
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