A Facile One-Pot Synthesis of Functionalized 1,3-Oxathiolan-2-Yliden Derivatives: Multicomponent Reaction of Oxiranes in Water

Faramarz      Rostami-Charati; Mohammad   R.   Hosseini-Tabatabaei; Mehdi      Shahraki

doi:10.2174/13862073113169990037

Abstract

An efficient synthesis of 1,3-oxathiolan-2-yliden derivatives is described via a simple reactions between CHacids, CS₂ and oxiranes in the presence of triethylamine at 70^oC in water as the solvent. The mild reaction conditions and high yields of the products exhibit the good synthetic advantage of this method.

Keywords: 1, 3-oxathiolan-2-yliden, one-pot reactions, oxirane, triethylamine.

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Combinatorial Chemistry & High Throughput Screening

Title:A Facile One-Pot Synthesis of Functionalized 1,3-Oxathiolan-2-Yliden Derivatives: Multicomponent Reaction of Oxiranes in Water

Volume: 17 Issue: 1

Author(s): Faramarz Rostami-Charati, Mohammad R. Hosseini-Tabatabaei and Mehdi Shahraki

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Keywords: 1, 3-oxathiolan-2-yliden, one-pot reactions, oxirane, triethylamine.

Abstract: An efficient synthesis of 1,3-oxathiolan-2-yliden derivatives is described via a simple reactions between CHacids, CS₂ and oxiranes in the presence of triethylamine at 70^oC in water as the solvent. The mild reaction conditions and high yields of the products exhibit the good synthetic advantage of this method.

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Rostami-Charati Faramarz, Hosseini-Tabatabaei R. Mohammad and Shahraki Mehdi, A Facile One-Pot Synthesis of Functionalized 1,3-Oxathiolan-2-Yliden Derivatives: Multicomponent Reaction of Oxiranes in Water, Combinatorial Chemistry & High Throughput Screening 2014; 17 (1) . https://dx.doi.org/10.2174/13862073113169990037