Separation of Ginseng Active Ingredients and their Roles in Cancer Metastasis Supplementary Therapy

Title:Separation of Ginseng Active Ingredients and their Roles in Cancer Metastasis Supplementary Therapy

Volume: 14 Issue: 5

Author(s): Jingjing Xie, Jingwei Shao, Yusheng Lu, Jianzhong Chen, Jichuang Wang, Suhong Yu and Lee Jia

Affiliation:

Keywords: Ginseng, ginsenosides, nutraceuticals, cancer prevention, metastasis.

Abstract: In Traditional Chinese Medicine (TCM), ginseng roots are taken orally as a pharmacological adaptogen and nourishing stimulants for thousands of years. Along with the rapid advancement of modern life technologies, ginseng’s effects as a non-toxic non-organspecific cancer preventive agent have recently been elucidated both at molecular levels and on clinical aspects. Here we presented some techniques used for separating ginseng active ingredients, evidence of effects of ginseng and its ingredients on cancer and cancer metastasis obtained from in vitro and in vivo experiments and thousands of volunteers participated in various clinical trials. As a biological response modifier and an adaptogen to synergistically enhance efficacy of conventional therapy as a supplement, adequate ginseng consumption reduces the risk of development of all types of cancer and the recurrence of some types of cancer, improves host intrinsic response to cancer and quality of patients’ life. We also briefly stated recent case reports on potential interaction between warfarin and ginseng products.

Cite this article as:

Xie Jingjing, Shao Jingwei, Lu Yusheng, Chen Jianzhong, Wang Jichuang, Yu Suhong and Jia Lee, Separation of Ginseng Active Ingredients and their Roles in Cancer Metastasis Supplementary Therapy, Current Drug Metabolism 2013; 14 (5) . https://dx.doi.org/10.2174/13892002113149990003