Facile N-Nitrosation of Secondary Amines Using Poly(N,N'-dibromo-Nethylene- benzene-1,3-disulfonamide)and N,N,N',N'-tetrabromobenzene- 1,3-disulfonamide/NaNO₂ Under Mild Conditions

Title:Facile N-Nitrosation of Secondary Amines Using Poly(N,N'-dibromo-Nethylene- benzene-1,3-disulfonamide)and N,N,N',N'-tetrabromobenzene- 1,3-disulfonamide/NaNO₂ Under Mild Conditions

Volume: 10 Issue: 3

Author(s): Ramin Ghorbani-Vaghei, Lotfi Shiri and Arash Ghorbani-Choghamarani

Affiliation:

Keywords: Poly (N, N'-Dibromo-N-ethylene-benzene-1, 3-disulfonamide) [PBBS], N, N, N', N'-tetrabromobenzene-1, 3-disulfonamide [TBBDA], N-Nitrosation, N-Nitrosamines, Sodium nitrite, Wet SiO₂

Abstract: In this research project, a combination of poly(N,N'-dibromo-N-ethylene-benzene-1,3-disulfonamide) [PBBS] and/or(N,N,N',N'-tetrabromobenzene-1,3-disulfonamide) [TBBDA] with sodium nitrite in the presence of wet SiO2 (50% w/w) was used as an efficient nitrosating agent for the conversion of secondary amines to their corresponding nitroso compounds. N-Nitrosation reaction has been performed in dichloromethane at room temperature under mild and heterogeneous conditions. The reaction is operationally simple and corresponding products were achieved in good to excellent yields.

Cite this article as:

Ghorbani-Vaghei Ramin, Shiri Lotfi and Ghorbani-Choghamarani Arash, Facile N-Nitrosation of Secondary Amines Using Poly(N,N'-dibromo-Nethylene- benzene-1,3-disulfonamide)and N,N,N',N'-tetrabromobenzene- 1,3-disulfonamide/NaNO₂ Under Mild Conditions, Letters in Organic Chemistry 2013; 10 (3) . https://dx.doi.org/10.2174/1570178611310030011