Abstract
In light of rapid progress in biochemistry and modern bioengineering, there is a great interest in understanding how modifying the structure of naturally occurring lipids can be used to improve their nutritional and health properties. Structured lipids (SLs) or custom-made lipids can supply functional fatty acids because of their specific positioning in the glycerol structure. Health benefits of n–3 fatty acids such as docosahexaenoic acid (DHA) have been widely reported. Little information is available on the potential for health benefits of the SLs molecules that are rich in DHA and have well defined structure. This review attempts to summarize our present state of knowledge of various approaches to produce structured DHA–containing triglycerides and phospholipids as well as their applications.
Current Organic Chemistry
Title:Synthesis and Biological Interest of Structured Docosahexaenoic Acid–Containing Triacylglycerols and Phospholipids
Volume: 17 Issue: 8
Author(s): Madeleine Picq, Nathalie Bernoud-Hubac and Michel Lagarde
Affiliation:
Keywords: Chemistry, DHA, lipids, fat, lipase, nutrition.
Abstract: In light of rapid progress in biochemistry and modern bioengineering, there is a great interest in understanding how modifying the structure of naturally occurring lipids can be used to improve their nutritional and health properties. Structured lipids (SLs) or custom-made lipids can supply functional fatty acids because of their specific positioning in the glycerol structure. Health benefits of n–3 fatty acids such as docosahexaenoic acid (DHA) have been widely reported. Little information is available on the potential for health benefits of the SLs molecules that are rich in DHA and have well defined structure. This review attempts to summarize our present state of knowledge of various approaches to produce structured DHA–containing triglycerides and phospholipids as well as their applications.
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Picq Madeleine, Bernoud-Hubac Nathalie and Lagarde Michel, Synthesis and Biological Interest of Structured Docosahexaenoic Acid–Containing Triacylglycerols and Phospholipids, Current Organic Chemistry 2013; 17 (8) . https://dx.doi.org/10.2174/1385272811317080009
DOI https://dx.doi.org/10.2174/1385272811317080009 |
Print ISSN 1385-2728 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5348 |
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Catalytic C-H bond activation as a tool for functionalization of heterocycles
The major topic is the functionalization of heterocycles through catalyzed C-H bond activation. The strategies based on C-H activation not only provide straightforward formation of C-C or C-X bonds but, more importantly, allow for the avoidance of pre-functionalization of one or two of the cross-coupling partners. The beneficial impact of ...read more
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