Preclinical and Clinical Studies on the Use of Stem Cells for Bone Repair: A Systematic Review

Title:Preclinical and Clinical Studies on the Use of Stem Cells for Bone Repair: A Systematic Review

Volume: 8 Issue: 3

Author(s): Anuruthran Ambikaipalan, James Min-Leong Wong and Wasim S. Khan

Affiliation:

Keywords: Bone repair, scaffolds, stem cells, tissue engineering

Abstract: The management of extensive bone defects in the setting of fracture repair, non-union and revision arthroplasty are challenging problems. The supply of harvestable autologous bone graft is limited, with an associated morbidity, and therefore a need exists for a better solution in large defects. The use of stem cells is an evolving field of research, with different potential applications, ranging from simple injection of cells to tissue engineering using osteogenic cells seeded onto a scaffold.

Cite this article as:

Ambikaipalan Anuruthran, Min-Leong Wong James and S. Khan Wasim, Preclinical and Clinical Studies on the Use of Stem Cells for Bone Repair: A Systematic Review, Current Stem Cell Research & Therapy 2013; 8 (3) . https://dx.doi.org/10.2174/1574888X11308030005