An Efficiently Sonochemical Synthesis of Novel Pyrazoles, Bipyrazoles and Pyrazol-3- ylPyrazolo[3,4-d]pyrimidines Incorporating 1H-benzoimidazole Moiety

Title:An Efficiently Sonochemical Synthesis of Novel Pyrazoles, Bipyrazoles and Pyrazol-3- ylPyrazolo[3,4-d]pyrimidines Incorporating 1H-benzoimidazole Moiety

Volume: 17 Issue: 2

Author(s): Nesreen S. Ahmed, Tamer S. Saleh and El-Sayed H. El-Mossalamy

Affiliation:

Keywords: Pyrazoles, Bipyrazoles, Benzimidazole, Ultrasonic irradiation, Pyrazolo[3, 4-d]pyrimidine

Abstract: Novel pyrazoles, bipyrazoles and pyrazol-3-ylpyrazolo[3,4-d]pyrimidines were synthesized using the versatil synthon 2-(1Hbenzimidazol- 2-yl)-3,3-bis(methylthio) acrylonitrile (1). Reactions were carried out under silent and ultrasonic conditions. In general, improvement in rates and yields were observed when reactions were carried out under ultrasonic irradiation compared with silent condition. Structures of the products were established on analytical and spectral data.

Cite this article as:

S. Ahmed Nesreen, S. Saleh Tamer and H. El-Mossalamy El-Sayed, An Efficiently Sonochemical Synthesis of Novel Pyrazoles, Bipyrazoles and Pyrazol-3- ylPyrazolo[3,4-d]pyrimidines Incorporating 1H-benzoimidazole Moiety, Current Organic Chemistry 2013; 17 (2) . https://dx.doi.org/10.2174/1385272811317020016