A General Simple Methodology for Synthesis of Isonitriles Using Benzene- 1,3-disulfonyl Dichloride

Ramin      Ghorbani-Vaghei; Mostafa      Amiri; Hojat      Veisi

doi:10.2174/1570178611310010010

Abstract

Isonitrile derivatives have been synthesized in good to high yields by dehydration of aliphatic and aromatic formamides in the presence of benzene-1,3-disulfonyl dichloride as easy and efficient reagent.

Keywords: Benzene-1, 3-disulfonylchloride (BDS), isonitrile, multicomponent reactions (MCRs), triethylamine (TEA), Isocyanide-based, isonitriles, anion, formamides, temperature, BDD

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Letters in Organic Chemistry

Title:A General Simple Methodology for Synthesis of Isonitriles Using Benzene- 1,3-disulfonyl Dichloride

Volume: 10 Issue: 1

Author(s): Ramin Ghorbani-Vaghei, Mostafa Amiri and Hojat Veisi

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Keywords: Benzene-1, 3-disulfonylchloride (BDS), isonitrile, multicomponent reactions (MCRs), triethylamine (TEA), Isocyanide-based, isonitriles, anion, formamides, temperature, BDD

Abstract: Isonitrile derivatives have been synthesized in good to high yields by dehydration of aliphatic and aromatic formamides in the presence of benzene-1,3-disulfonyl dichloride as easy and efficient reagent.

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Ghorbani-Vaghei Ramin, Amiri Mostafa and Veisi Hojat, A General Simple Methodology for Synthesis of Isonitriles Using Benzene- 1,3-disulfonyl Dichloride, Letters in Organic Chemistry 2013; 10 (1) . https://dx.doi.org/10.2174/1570178611310010010