Advances in Studies on the Rupestonic Acid Derivatives as Anti-influenza Agents

Jianping      Yong; Canzhong      Lu; Haji      Akber Aisa

doi:10.2174/1389557511313020012

Abstract

Rupestonic acid (isolated from the Chinese traditional medicine Artemisia rupestris L.) is a sesquiterpene with multifunctional groups and possess higher activity against influenza virus B. In order to improve the biological activity of rupestonic acid, many derivatives have been synthesized and their anti-influenza activity was screened. This review describes the rupestonic acid derivatives and their anti-influenza activity studied by our researching group.

Keywords: Rupestonic acid derivatives, anti-influenza virus, structure-activity relationship

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Mini-Reviews in Medicinal Chemistry

Title:Advances in Studies on the Rupestonic Acid Derivatives as Anti-influenza Agents

Volume: 13 Issue: 2

Author(s): Jianping Yong, Canzhong Lu and Haji Akber Aisa

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Keywords: Rupestonic acid derivatives, anti-influenza virus, structure-activity relationship

Abstract: Rupestonic acid (isolated from the Chinese traditional medicine Artemisia rupestris L.) is a sesquiterpene with multifunctional groups and possess higher activity against influenza virus B. In order to improve the biological activity of rupestonic acid, many derivatives have been synthesized and their anti-influenza activity was screened. This review describes the rupestonic acid derivatives and their anti-influenza activity studied by our researching group.

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Yong Jianping, Lu Canzhong and Akber Aisa Haji, Advances in Studies on the Rupestonic Acid Derivatives as Anti-influenza Agents, Mini-Reviews in Medicinal Chemistry 2013; 13 (2) . https://dx.doi.org/10.2174/1389557511313020012