Abstract
The pharmacological importance of substituted 1,4-and 1,5-benzodiazepines has been well established and some derivatives are known as anxiolytic, anticonvulsant, hypnotic and anticancer agents. In recent years, much effort has been done in the benzodiazepine area to develop new members of this family. This review focuses on the synthesis and the biological activities of benzodiazepam derivatives.
Keywords: Anticonvulsant, Anxiolytic, Anticancer agents, Benzodiazepam, Biological activities, Synthesis.