Abstract
1,4-Dihydropyridines are excellent precursors of various pharmacologically important molecules which possess calcium channel blocking activity. The synthesis of various 1,4-dihydro pyridines and their importance is reviewed for the first time to our knowledge.
Keywords: electron-withdrawing groups, 4-unsubstituted pyridine, calcium antagonists, vasodilation, hypertension
Call for Papers in Thematic Issues
Catalytic C-H bond activation as a tool for functionalization of heterocycles
The major topic is the functionalization of heterocycles through catalyzed C-H bond activation. The strategies based on C-H activation not only provide straightforward formation of C-C or C-X bonds but, more importantly, allow for the avoidance of pre-functionalization of one or two of the cross-coupling partners. The beneficial impact of ...read more
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