Stereoselective Biotransformations as an Effective Tool for the Synthesis of Chiral Compounds with P-C Bond – Scope and Limitations of the Methods

Ewa      Zymanczyk-Duda; Magdalena      Klimek-Ochab

doi:10.2174/138527212800672628

Abstract

This article discusses advantages and limitations of the biotransformations with enzymes and whole-cell catalysts. It reviews biocatalytic synthesis of the chiral, organophosphorus compounds of different structures and characterizes their biological importance.

Keywords: Organophosphonates, Stereoselective biotransformations, Biocatalysts

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Current Organic Chemistry

Title:Stereoselective Biotransformations as an Effective Tool for the Synthesis of Chiral Compounds with P-C Bond – Scope and Limitations of the Methods

Volume: 16 Issue: 11

Author(s): Ewa Zymanczyk-Duda and Magdalena Klimek-Ochab

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Keywords: Organophosphonates, Stereoselective biotransformations, Biocatalysts

Abstract: This article discusses advantages and limitations of the biotransformations with enzymes and whole-cell catalysts. It reviews biocatalytic synthesis of the chiral, organophosphorus compounds of different structures and characterizes their biological importance.

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Zymanczyk-Duda Ewa and Klimek-Ochab Magdalena, Stereoselective Biotransformations as an Effective Tool for the Synthesis of Chiral Compounds with P-C Bond – Scope and Limitations of the Methods, Current Organic Chemistry 2012; 16 (11) . https://dx.doi.org/10.2174/138527212800672628