Heparin - a Key Drug in the Treatment of the Circulatory Degenerative Diseases: Controlling its Action with Polymers

Title:Heparin - a Key Drug in the Treatment of the Circulatory Degenerative Diseases: Controlling its Action with Polymers

Volume: 18 Issue: 18

Author(s): Krzysztof Szczubialka, Kamil Kaminski, Katarzyna Zasada, Anna Karewicz and Maria Nowakowska

Affiliation:

Keywords: Heparin, anticoagulation, unfractionated heparin, low molecular weight heparin, heparin reversal, noninvasive delivery, heparinotherapy, heparin inhibition, polymeric substances, glycosaminoglycans (GAGs)

Abstract: The properties of heparin, a key anticoagulant, are reviewed. The important issues in heparinotherapy, i.e., reaching quick anticoagulant effect, maintaining therapeutic level of anticoagulation, heparin inhibition and non-invasive heparin formulations have been reviewed and discussed, with the focus on the role of polymeric substances in the proposed solutions.

Cite this article as:

Szczubialka Krzysztof, Kaminski Kamil, Zasada Katarzyna, Karewicz Anna and Nowakowska Maria, Heparin - a Key Drug in the Treatment of the Circulatory Degenerative Diseases: Controlling its Action with Polymers, Current Pharmaceutical Design 2012; 18 (18) . https://dx.doi.org/10.2174/138161212800492840