Sleep-Inducing Factors

Title: Sleep-Inducing Factors

Volume: 8 Issue: 4

Author(s): Fabio Garcia-Garcia, Eva Acosta-Pena, Arturo Venebra-Munoz and Eric Murillo-Rodriguez

Affiliation:

Keywords: Humoral sleep regulation, Stress, purine, cannabinoids

Abstract: Kuniomi Ishimori and Henri Piéron were the first researchers to introduce the concept and experimental evidence for a chemical factor that would presumably accumulate in the brain during waking and eventually induce sleep. This substance was named hypnotoxin. Currently, the variety of substances which have been shown to alter sleep includes peptides, cytokines, neurotransmitters and some substances of lipidic nature, many of which are well known for their involvement in other biological activities. In this chapter, we describe the sleep-inducing properties of the vasoactive intestinal peptide, prolactin, adenosine and anandamide.

Cite this article as:

Garcia-Garcia Fabio, Acosta-Pena Eva, Venebra-Munoz Arturo and Murillo-Rodriguez Eric, Sleep-Inducing Factors, CNS & Neurological Disorders - Drug Targets 2009; 8 (4) . https://dx.doi.org/10.2174/187152709788921672