Abstract
Much interest has focused on the newer incretin-based therapeutic modalities for diabetes, especially GLP-1 analogues. While the comparatively older GLP-1 analogs, exenatide and liraglutide, have been discussed extensively in literature, much less is known about the newer GLP-1 analogues in the pipeline. This review focuses on the newer molecules being studied, the newer routes of administration being tried, some recent patents and potential uses for these multifaceted compounds.
Keywords: GLP-1 analogs, long acting exenatide, albiglutide, taspoglutide, GLP-2 analogs, GLP-1 secretagogues
Recent Patents on Endocrine, Metabolic & Immune Drug Discovery (Discontinued)
Title: GLP - 1 Analogs: Newer Molecules, Newer Uses
Volume: 3 Issue: 2
Author(s): Sanjay Kalra, Bharti Kalra and Amit Kumar
Affiliation:
Keywords: GLP-1 analogs, long acting exenatide, albiglutide, taspoglutide, GLP-2 analogs, GLP-1 secretagogues
Abstract: Much interest has focused on the newer incretin-based therapeutic modalities for diabetes, especially GLP-1 analogues. While the comparatively older GLP-1 analogs, exenatide and liraglutide, have been discussed extensively in literature, much less is known about the newer GLP-1 analogues in the pipeline. This review focuses on the newer molecules being studied, the newer routes of administration being tried, some recent patents and potential uses for these multifaceted compounds.
Export Options
About this article
Cite this article as:
Kalra Sanjay, Kalra Bharti and Kumar Amit, GLP - 1 Analogs: Newer Molecules, Newer Uses, Recent Patents on Endocrine, Metabolic & Immune Drug Discovery (Discontinued) 2009; 3 (2) . https://dx.doi.org/10.2174/187221409788452309
DOI https://dx.doi.org/10.2174/187221409788452309 |
Print ISSN 1872-2148 |
Publisher Name Bentham Science Publisher |
Online ISSN 2212-3334 |
Related Articles
-
Cardiac Aging and Insulin Resistance: Could Insulin/Insulin-Like Growth Factor (IGF) Signaling be used as a Therapeutic Target?
Current Pharmaceutical Design Phosphodiesterase-5 Inhibitors: Future Perspectives
Current Pharmaceutical Design Vitamins B1, B2, B3 and B9 – Occurrence, Biosynthesis Pathways and Functions in Human Nutrition
Mini-Reviews in Medicinal Chemistry Advances in Chagas Disease Chemotherapy
Anti-Infective Agents in Medicinal Chemistry Cardiac Remodeling Induced by Smoking: Concepts, Relevance, and Potential Mechanisms
Inflammation & Allergy - Drug Targets (Discontinued) Protein-mediated Fatty Acid Uptake in the Heart
Current Cardiology Reviews Therapy Against Ischemic Injury
Current Pharmaceutical Design Amniotic Fluid Embolism: Moving Diagnosis Through the Time. From the Mechanical Pulmonary Vascular Occlusion Until An Immuno - Inflammatory Pathogenesis?
Current Pharmaceutical Biotechnology Endoplasmic Reticulum Stress, Diabetes Mellitus, and Tissue Injury
Current Protein & Peptide Science Ferroptotic Cell Death: New Regulatory Mechanisms for Metabolic Diseases
Endocrine, Metabolic & Immune Disorders - Drug Targets Chelating Agents for Metal Intoxication
Current Medicinal Chemistry Safety Analysis and Improved Cardiac Function Following Local Autologous Transplantation of CD133+ Enriched Bone Marrow Cells After Myocardial Infarction
Current Neurovascular Research Noninvasive Diagnosis of Chemotherapy Related Cardiotoxicity
Current Cardiology Reviews Chaperones and Cardiac Misfolding Protein Diseases
Current Protein & Peptide Science Testosterone and Cardioprotection Against Myocardial Ischemia
Cardiovascular & Hematological Disorders-Drug Targets Potential Therapeutic Benefits of Sodium-Glucose Cotransporter 2 Inhibitors in the Context of Ischemic Heart Failure: A State-of-the-Art Review
Cardiovascular & Hematological Agents in Medicinal Chemistry Cardiac Nuclear Imaging: Current Status and Future Directions
Current Medical Imaging Apoptosis and Oxidative Stress-Related Diseases: The p66Shc Connection
Current Molecular Medicine Synthesis, Docking and Antidiabetic Activity of Some Newer Benzamide Derivatives as Potential Glucokinase Activators
Letters in Drug Design & Discovery Editorial (Thematic Issue: Current Topics in Pharmacogenomics)
Recent Patents on Biotechnology