Advances in Drug Discovery to Assess Cholinergic Neurotransmission: A Systematic Review

Title: Advances in Drug Discovery to Assess Cholinergic Neurotransmission: A Systematic Review

Volume: 5 Issue: 3

Author(s): Vitor F. Ferreira, David R. da Rocha, Katia G. Lima Araujo and Wilson C. Santos

Affiliation:

Keywords: Cholinergic neurotransmission, cholinergic receptors, carbohydrates

Abstract: Neurotransmission is essential to physiological processes of cellular communication. The search for new molecules that may influence neurotransmission systems is an open field with possible impact on several pathophysiological conditions or diseases: Alzheimers disease, Parkinsonism and myasthenia gravis, etc. The present review describes the most important aspects of cholinergic neurotransmission, as well as natural and synthetic compounds that, as clinical or experimental drugs, are able to influence this transmission. The pharmacological effects of substances that bind to muscarinic or nicotinic cholinergic receptors, along with their corresponding affinities will also be presented.

Cite this article as:

Ferreira F. Vitor, da Rocha R. David, Lima Araujo G. Katia and Santos C. Wilson, Advances in Drug Discovery to Assess Cholinergic Neurotransmission: A Systematic Review, Current Drug Discovery Technologies 2008; 5 (3) . https://dx.doi.org/10.2174/157016308785739848