Abstract
Cholecystokinin (CCK) receptors are divided into CCK-1 (formerly CCK-A) and CCK-2 (formerly CCK-B) sub-types. CCK is a widely distributed neuropeptide in the brain and is considered a central nervous system transmitter. Possible therapeutic applications for CCK-2 antagonists include panic, anxiety, analgesia, schizophrenia, gastric disorders, and gastrointestinal tumours. This review covers the last five years findings in the field of such molecules
Keywords: cck-2 antagonists, cck-b antagonists, cholecystokinin, neuropeptide, panic,analgesic, schizophrenia,anxiety