Abstract
Asthma and chronic obstructive pulmonary disease (COPD) are common chronic disorders. Traditionally, asthma has been associated with an eosinophilic inflammation and COPD with neutrophilic inflammation. In this review we will highlight the maturation, recruitment, activation, action and apoptosis of these cells. In addition we will focus on the evidence for their presence in disease and suggest potential new therapeutic interventions.
Keywords: asthma, copd, eosinophils, neutrophils
Current Drug Targets - Inflammation & Allergy
Title: Neutrophils and Eosinophils: Clinical Implications of their Appearance, Presence and Disappearance in Asthma and COPD
Volume: 4 Issue: 4
Author(s): A. P. Watt, B. C. Schock and M. Ennis
Affiliation:
Keywords: asthma, copd, eosinophils, neutrophils
Abstract: Asthma and chronic obstructive pulmonary disease (COPD) are common chronic disorders. Traditionally, asthma has been associated with an eosinophilic inflammation and COPD with neutrophilic inflammation. In this review we will highlight the maturation, recruitment, activation, action and apoptosis of these cells. In addition we will focus on the evidence for their presence in disease and suggest potential new therapeutic interventions.
Export Options
About this article
Cite this article as:
Watt P. A., Schock C. B. and Ennis M., Neutrophils and Eosinophils: Clinical Implications of their Appearance, Presence and Disappearance in Asthma and COPD, Current Drug Targets - Inflammation & Allergy 2005; 4 (4) . https://dx.doi.org/10.2174/1568010054526313
DOI https://dx.doi.org/10.2174/1568010054526313 |
Print ISSN 1568-010X |
Publisher Name Bentham Science Publisher |
Online ISSN 1568-010X |
Related Articles
-
Dietary Antioxidants Significantly Reduced Phorbol Myristate Acetate Induced Oxidative Stress of Peripheral Blood Mononuclear Cells of Patients with Rheumatoid Arthritis
Current Rheumatology Reviews TGF-β: Its Role in Asthma and Therapeutic Potential
Current Drug Targets Acetylcholinesterase Inhibitors and Drugs Acting on Muscarinic Receptors- Potential Crosstalk of Cholinergic Mechanisms During Pharmacological Treatment
Current Neuropharmacology Medicinal Chemistry of Selective Neurokinin-1 Antagonists
Current Topics in Medicinal Chemistry Nanoparticle-Based Diagnosis and Therapy
Current Drug Targets Antioxidant Properties of Kalanchoe blossfeldiana – A Focus on Erythrocyte Membrane Stability and Cytoprotection
Current Traditional Medicine Modifiable Risk Factors Associated with Alzheimer’s Disease with Special Reference to Sleep Disturbance
CNS & Neurological Disorders - Drug Targets Dynamics of CD86 Expression on Allergic Inflammation - New Insights
Recent Patents on Inflammation & Allergy Drug Discovery A Novel Synthesis of p-Nitrobenzylphosphonic Acid and its Action on Alkaline Phosphatase
Letters in Organic Chemistry Patent Selections:
Recent Patents on Drug Delivery & Formulation Mobile Phone Based Health Care Technology
Recent Patents on Biomedical Engineering (Discontinued) Biologics in Children with Allergic Diseases
Current Pediatric Reviews The Role of Tregs in Cancer: Foxp3 as a Putative Target for Therapy
Current Signal Transduction Therapy Comparison of Triflusal with Aspirin in the Secondary Prevention of Atherothrombotic Events; Α Randomised Clinical Trial
Current Vascular Pharmacology Thrombomodulin – A New Target for Treating Stroke at the Crossroad of Coagulation and Inflammation
Current Medicinal Chemistry Occupational Exposure and COPD
Current Respiratory Medicine Reviews Nucleic Acids as Therapeutic Agents
Current Topics in Medicinal Chemistry Age-Related Pharmacokinetic and Pharmacodynamic Changes and Related Risk of Adverse Drug Reactions
Current Medicinal Chemistry Docking-based 3D-QSAR Studies of Phosphodiesterase 9A Inhibitors
Letters in Drug Design & Discovery Neuroimmune Crosstalk in CNS Disorders: The Histamine Connection
Current Pharmaceutical Design