Copper-Catalyzed Nitration of Arylboronic Acids with Nitrite Salts Under Mild Conditions: An Efficient Synthesis of Nitroaromatics

Title: Copper-Catalyzed Nitration of Arylboronic Acids with Nitrite Salts Under Mild Conditions: An Efficient Synthesis of Nitroaromatics

Volume: 9 Issue: 2

Author(s): Guobing Yan, Ling Zhang and Jian Yu

Affiliation:

Keywords: Arylboronic acids, copper catalyst, nitration, nitroaromatics, organic synthesis, pharmaceuticals, iodides, chlorotrimethylsilane, oxidative, cross-coupling

Abstract: Copper-catalyzed nitration of arylboronic acids has been developed with nitrite salts as nitrating agent under mild conditions. This process provides an efficient and practical method for the synthesis of nitro aromatics, due to its simple experimental procedure and its use of convenient and inexpensive copper catalyst.

Cite this article as:

Yan Guobing, Zhang Ling and Yu Jian, Copper-Catalyzed Nitration of Arylboronic Acids with Nitrite Salts Under Mild Conditions: An Efficient Synthesis of Nitroaromatics, Letters in Organic Chemistry 2012; 9 (2) . https://dx.doi.org/10.2174/157017812800221717