Three Component Condensation Reaction as an Efficient Route for the Synthesis of Furo[2,3-d]pyrimidines

Title: Three Component Condensation Reaction as an Efficient Route for the Synthesis of Furo[2,3-d]pyrimidines

Volume: 9 Issue: 1

Author(s): Ali Aminkhani and Ghasem Marandi

Affiliation:

Keywords: Aldehydes, condensation reaction, fused heterocycles, isocyanides, 1,3-dimethylbarbituric acid, 1,3-dimethylfuro[2,3-d]pyrimidine, N-methyl groups, anti-inflammatory, antiviral, anti HIV

Abstract: The condensation reactions of alkyl isocyanides with 1,3-dimethylbarbituric acid and aryl carboxaldehydes to afford 6-(alkylamino)-5-(3-aryl)-1,3-dimethylfuro[2,3-d]pyrimidine-2,4(1H,3H)-dione, in excellent yields under neutral conditions, are reported.

Cite this article as:

Aminkhani Ali and Marandi Ghasem, Three Component Condensation Reaction as an Efficient Route for the Synthesis of Furo[2,3-d]pyrimidines, Letters in Organic Chemistry 2012; 9 (1) . https://dx.doi.org/10.2174/157017812799304079