Quinolone Dimers as Potential Antibacterial Agents

Naveenkumar      R. Chepyala; Rajashaker      R. Durgi; Lakshmi      K. Tatini; Gottumukkala      V. Subbaraju; Rama      M. Hindupur; Muralimohan      R. Dhanvada

doi:10.2174/157017811799304322

Abstract

A series of novel 6-fluoro1,4-dihydro-4-oxo-3-quinoline carboxylic acid dimers (34-37), were synthesized as potential antibacterial agents from commercially available fluoro benzoic acids.

Keywords: 2,3,4,5-Tetraflurobenzoic acid, 2,4,5-Trifluoroacetophenone, anti bacterial agents, regiospecific dimeric cyclisation, STERMOL length, quinoline carboxylic acid dimers, cyclopropyl, ciprofloxacin., methylene, ofloxacin

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Letters in Organic Chemistry

Title: Quinolone Dimers as Potential Antibacterial Agents

Volume: 8 Issue: 9

Author(s): Naveenkumar R. Chepyala, Rajashaker R. Durgi, Lakshmi K. Tatini, Gottumukkala V. Subbaraju, Rama M. Hindupur and Muralimohan R. Dhanvada

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Abstract: A series of novel 6-fluoro1,4-dihydro-4-oxo-3-quinoline carboxylic acid dimers (34-37), were synthesized as potential antibacterial agents from commercially available fluoro benzoic acids.

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R. Chepyala Naveenkumar, R. Durgi Rajashaker, K. Tatini Lakshmi, V. Subbaraju Gottumukkala, M. Hindupur Rama and R. Dhanvada Muralimohan, Quinolone Dimers as Potential Antibacterial Agents, Letters in Organic Chemistry 2011; 8 (9) . https://dx.doi.org/10.2174/157017811799304322