Development of Sugar-Based Materials for Biological Devices

Yuji      Mikata; Shigenobu      Yano

doi:10.2174/156802612799079017

Abstract

Recent progresses of our group dealing with newly developed sugar-based ligands and their metal complexes have been reviewed. Carbohydrate moiety affects on the stereochemistry around the metal center and controls the biological activity of the complex.

Keywords: Carbohydrates, metal, porphyrin, nucleic acids, biological activity of the complex, macrocycles, β-lactams, β-C-glycosylation, bioactive molecules, metal complexes, peptide synthesis, anomeric oxygen atoms, peptide-based drug candidates, apical atoms