Potential New Anticancer Molecular Targets for the Treatment of Human Testicular Seminomas

P.      Chieffi

doi:10.2174/138955711797247770

Abstract

In the last years novel therapeutic approaches for the treatment of cancer have been proposed: specific inhibitors of serine/threonine and tyrosine kinases, angiogenesis inhibitors, antibodies against receptors/surface molecules on cancer cells, gene therapy approaches and others. In a lot of cases the clinical trials have confirmed the efficacy of these approaches.

Here, we will review the discovered new potential molecular targets for the treatment of human testicular seminomas.

Keywords: Testis, testicular cancer, gonocytes, testicular germ cells, seminomas, tyrosine kinases, angiogenesis inhibitors, antibodies, serine/threonine, molecular targets