Synthesis of Mycinose from 1,2:5,6-Di-O-Isopropylidene-α-D-glucofuranose

Title: Synthesis of Mycinose from 1,2:5,6-Di-O-Isopropylidene-α-D-glucofuranose

Volume: 8 Issue: 8

Author(s): Kai Bao, Hao Gao, Zhibin Zhu, Jinhong Wang, Guoning Zhang, Jun Sun, Weige Zhang and Xinsheng Yao

Affiliation:

Keywords: 1,2:5,6-Di-O-Isopropylidene-α-D-glucofuranose, debromination, mycinose, synthesis, glucofuranose, stoichiometry, hydroxyl group, Microwave assisted deprotection, spectroscopy, sodium borohydride

Abstract: A facile synthesis of mycinose from commercially available 1,2:5,6-Di-O-isopropylidene-α-D-glucofuranose was developed. A selective and direct reductive debromination of α-hydroxy bromides in a simple NaBH4/EtOH/H2O system was found.

Cite this article as:

Bao Kai, Gao Hao, Zhu Zhibin, Wang Jinhong, Zhang Guoning, Sun Jun, Zhang Weige and Yao Xinsheng, Synthesis of Mycinose from 1,2:5,6-Di-O-Isopropylidene-α-D-glucofuranose, Letters in Organic Chemistry 2011; 8 (8) . https://dx.doi.org/10.2174/157017811797249290