α-Hydroxyiminophosphonate, -phosphinate and -phosphonium Derivatives

Title: α-Hydroxyiminophosphonate, -phosphinate and -phosphonium Derivatives

Volume: 7 Issue: 6

Author(s): Javier Vicario, Concepcion Alonso, Jesus M. de los Santos and Francisco Palacios

Affiliation:

Keywords: Iminophosphonates, iminophosphinates, iminophosphonium salts, aminophosphonic acids, Beckmann rearrangement

Abstract: The structural and synthetic aspects related to α-oxyiminophosphorus derivatives are reviewed. This includes their preparation through reactions involving C-N double bond or P-C single bond formation as well as the O-functionalization or transformations at the phosphorus atom of other phosphorus substituted oximes. Moreover the synthetic features of α-oxyiminophosphorus derivatives include the reduction of the oximo group with selective preparation of biologically active α-amino-phosphonate and -phosphinate derivatives, as well as the oxidative transformations on the oxime group, rearrangement versus fragmentation reactions, radical reactions and formation of metal complexes.

Cite this article as:

Vicario Javier, Alonso Concepcion, M. de los Santos Jesus and Palacios Francisco, α-Hydroxyiminophosphonate, -phosphinate and -phosphonium Derivatives, Current Organic Synthesis 2010; 7 (6) . https://dx.doi.org/10.2174/157017910794328583