Single Cell Proteomics: Challenge for Current Analytical Science

Title: Single Cell Proteomics: Challenge for Current Analytical Science

Volume: 2 Issue: 1

Author(s): Bo Xu, Wei Du, Bi-Feng Liu and Qingming Luo

Affiliation:

Keywords: Single cell proteomics, Protein separation, Chromatography, Capillary electrophoresis, Microfluidic chip, Review

Abstract: At present, proteomics that promises deep understanding of genomic functions is developing rapidly. Proteomics at single cell level represents new challenges that greatly call for technique innovation in current analytical chemistry. In this mini-review, the concept of single cell proteomics (SCP) is clarified. Recent advancement on strategy and methodology of SCP is reviewed, with emphasis on micro-separation technique improvement such as ultra-thin layer gel electrophoresis, multidimensional micro liquid chromatography and capillary electrophoresis, and microfluidic chip as well. Future development on SCP is also suggested.

Cite this article as:

Xu Bo, Du Wei, Liu Bi-Feng and Luo Qingming, Single Cell Proteomics: Challenge for Current Analytical Science, Current Analytical Chemistry 2006; 2 (1) . https://dx.doi.org/10.2174/157341106775197402