Regioselective Synthesis of Functionalized Oxime Ethers

Jun      Liu; Dafeng      Li; Jian      Li; Chunju      Li; Xueshun      Jia

doi:10.2174/157017810791824874

Abstract

We report in this paper the regioselective synthesis of functionalized oxime ethers 3 in good yields from the reaction of readily available starting material oximes with allyl bromides, derived from Baylis-Hillman adducts, in the presence of sodium hydride and triethyl amine under mild condition.

Keywords: Regioselective synthesis, Baylis-Hillman adduct, oxime, functionalized oxime ether

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Letters in Organic Chemistry

Title: Regioselective Synthesis of Functionalized Oxime Ethers

Volume: 7 Issue: 6

Author(s): Jun Liu, Dafeng Li, Jian Li, Chunju Li and Xueshun Jia

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Keywords: Regioselective synthesis, Baylis-Hillman adduct, oxime, functionalized oxime ether

Abstract: We report in this paper the regioselective synthesis of functionalized oxime ethers 3 in good yields from the reaction of readily available starting material oximes with allyl bromides, derived from Baylis-Hillman adducts, in the presence of sodium hydride and triethyl amine under mild condition.

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Liu Jun, Li Dafeng, Li Jian, Li Chunju and Jia Xueshun, Regioselective Synthesis of Functionalized Oxime Ethers, Letters in Organic Chemistry 2010; 7 (6) . https://dx.doi.org/10.2174/157017810791824874